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has agreed to a massive $950 million settlement with the U. government and 43 states over the way it marketed the painer Vioxx. Department of Justice said Merck will also plead guilty to misdemeanor charges that it marketed Vioxx as a treatment for arthritis before it gained approval to do so from the Food and Drug Administration (FDA).

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The popular arthritis drug was withdrawn from the market in 2004 after it was linked to increased risk of heart attack and stroke among those who took it. The criminal component of the agreement centers on the illegal marketing and promotion of Vioxx for the treatment of rheumatoid arthritis.

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Non-steroidal anti-inflammatory medicines (NSAIDs) have been around since the 1960s.

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Prescription NSAID medications -- including Celebrex, shown here -- are used to treat arthritis and other pain conditions.

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